PLATELETS AND BLOOD COAGULATION

Proteolytic enzymes and platelets in relation to blood coagulation.

Silica Nanoparticles Effects on Blood Coagulation Proteins and Platelets

Interaction of nanoparticles with the blood coagulation is important prior to their using as the drug carriers or therapeutic agents. The aim of present work was studying of the primary effects of silica nanoparticles (SiNPs) on haemostasis in vitro. We studied the effect of SiNPs on blood coagulation directly estimating the activation of prothrombin and factor X and to verify any possible effe...

Platelets and coagulation in infection

Disseminated intravascular coagulation (DIC) is a frequent complication in sepsis that is associated with worse outcomes and higher mortality in patients. In addition to the uncontrolled generation of thrombi throughout the patient's vasculature, DIC often consumes large quantities of clotting factors leaving the patient susceptible to hemorrhaging. Owing to these complications, patients often ...

Activation of platelets and coagulation

Ned Tijdschr Klin Chem Labgeneesk 2016, vol. 41, no. 1

Hemophilia. I. the Abnormal Coagulation of the Blood and Its Relation to the Blood Platelets.

The one abnormality constantly found in hemophilia is an inability of the blood to coagulate in a normal manner. This defect is demonstrable usually by a prolonged clotting time, which in turn determines the various manifestations of the disease. Further understanding of this disease depends, therefore, upon knowledge of the cause of the prolonged clotting time. Most investigations of the blood...